Thorne Advanced Digestive Enzymes
The gut is where performance nutrition either pays off or gets wasted. You can dial in your protein timing, take all the right supplements, and eat clean at every meal — but if your digestive system isn't producing enough of the right enzymes at the right stages, the nutrients in that food never fully reach your muscles.
Endurance athletes are especially vulnerable: high training volume suppresses digestive enzyme output, antacid overuse depletes stomach acid, and aging quietly slows production across the board. The result is incomplete digestion that shows up as bloating, gas, and the kind of fatigue that doesn't respond to more food or more rest.
Thorne Advanced Digestive Enzymes steps in at every stage of that process to make sure the nutrition you're eating is actually getting used.
Rebuild the Stomach Foundation – Betaine hydrochloride and L-glutamic acid hydrochloride work together to restore stomach acidity, while porcine-sourced pepsin activates in that acidic environment to begin protein breakdown. This upstream foundation determines everything downstream: adequate HCL triggers the release of pancreatic enzymes and bile, sterilizes ingested pathogens, and facilitates the absorption of key micronutrients including B12, folate, iron, and zinc.
Complete Macronutrient Breakdown – Pancreatin is the pancreas's contribution to digestion — a concentrated blend of amylase (carbohydrate digestion), lipase (fat digestion), and protease (protein digestion). When the stomach acid signal is adequate, the pancreas releases these enzymes into the small intestine. When it isn't, pancreatin production drops and macronutrient digestion becomes incomplete.
Unlock Your Fat-Soluble Nutrients – Bile emulsifies dietary fats and is the essential vehicle for absorbing fat-soluble vitamins A, D, E, and K, as well as CoQ10 and omega-3 fatty acids. Athletes who have had their gallbladder removed lose the bile reservoir entirely — but even those with an intact gallbladder can have compromised bile output from chronic low stomach acid. Ox bile concentrate in this formula directly fills that gap, enabling full absorption of the fat-soluble micronutrients your body depends on for immunity, bone health, and cardiovascular function.
Together these five ingredients — betaine HCL, L-glutamic acid HCL, pepsin, pancreatin, and ox bile — replicate the complete digestive enzyme environment that your body produces from mouth to small intestine. This is broad-spectrum support, not just an antacid or a single-enzyme product.
How to Use Thorne Advanced Digestive Enzymes
With Every Meal: Take 1–2 capsules with each meal, or as recommended by your healthcare practitioner. The capsules work during active digestion — taking them at the start of a meal is ideal.
Adjust by Meal Size and Composition: Larger meals — especially those high in protein or fat — may benefit from 2 capsules. Lighter meals may need only 1. Let your digestive response guide your dose.
Pro Tip: Do not open the capsule or remove the powder — betaine HCL and L-glutamic acid HCL are irritating to the mouth and esophagus. Always swallow whole.
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Thorne Advanced Digestive Enzymes
Thorne Advanced Digestive Enzymes
The gut is where performance nutrition either pays off or gets wasted. You can dial in your protein timing, take all the right supplements, and eat clean at every meal — but if your digestive system isn't producing enough of the right enzymes at the right stages, the nutrients in that food never fully reach your muscles.
Endurance athletes are especially vulnerable: high training volume suppresses digestive enzyme output, antacid overuse depletes stomach acid, and aging quietly slows production across the board. The result is incomplete digestion that shows up as bloating, gas, and the kind of fatigue that doesn't respond to more food or more rest.
Thorne Advanced Digestive Enzymes steps in at every stage of that process to make sure the nutrition you're eating is actually getting used.
Rebuild the Stomach Foundation – Betaine hydrochloride and L-glutamic acid hydrochloride work together to restore stomach acidity, while porcine-sourced pepsin activates in that acidic environment to begin protein breakdown. This upstream foundation determines everything downstream: adequate HCL triggers the release of pancreatic enzymes and bile, sterilizes ingested pathogens, and facilitates the absorption of key micronutrients including B12, folate, iron, and zinc.
Complete Macronutrient Breakdown – Pancreatin is the pancreas's contribution to digestion — a concentrated blend of amylase (carbohydrate digestion), lipase (fat digestion), and protease (protein digestion). When the stomach acid signal is adequate, the pancreas releases these enzymes into the small intestine. When it isn't, pancreatin production drops and macronutrient digestion becomes incomplete.
Unlock Your Fat-Soluble Nutrients – Bile emulsifies dietary fats and is the essential vehicle for absorbing fat-soluble vitamins A, D, E, and K, as well as CoQ10 and omega-3 fatty acids. Athletes who have had their gallbladder removed lose the bile reservoir entirely — but even those with an intact gallbladder can have compromised bile output from chronic low stomach acid. Ox bile concentrate in this formula directly fills that gap, enabling full absorption of the fat-soluble micronutrients your body depends on for immunity, bone health, and cardiovascular function.
Together these five ingredients — betaine HCL, L-glutamic acid HCL, pepsin, pancreatin, and ox bile — replicate the complete digestive enzyme environment that your body produces from mouth to small intestine. This is broad-spectrum support, not just an antacid or a single-enzyme product.
How to Use Thorne Advanced Digestive Enzymes
With Every Meal: Take 1–2 capsules with each meal, or as recommended by your healthcare practitioner. The capsules work during active digestion — taking them at the start of a meal is ideal.
Adjust by Meal Size and Composition: Larger meals — especially those high in protein or fat — may benefit from 2 capsules. Lighter meals may need only 1. Let your digestive response guide your dose.
Pro Tip: Do not open the capsule or remove the powder — betaine HCL and L-glutamic acid HCL are irritating to the mouth and esophagus. Always swallow whole.
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
The gut is where performance nutrition either pays off or gets wasted. You can dial in your protein timing, take all the right supplements, and eat clean at every meal — but if your digestive system isn't producing enough of the right enzymes at the right stages, the nutrients in that food never fully reach your muscles.
Endurance athletes are especially vulnerable: high training volume suppresses digestive enzyme output, antacid overuse depletes stomach acid, and aging quietly slows production across the board. The result is incomplete digestion that shows up as bloating, gas, and the kind of fatigue that doesn't respond to more food or more rest.
Thorne Advanced Digestive Enzymes steps in at every stage of that process to make sure the nutrition you're eating is actually getting used.
Rebuild the Stomach Foundation – Betaine hydrochloride and L-glutamic acid hydrochloride work together to restore stomach acidity, while porcine-sourced pepsin activates in that acidic environment to begin protein breakdown. This upstream foundation determines everything downstream: adequate HCL triggers the release of pancreatic enzymes and bile, sterilizes ingested pathogens, and facilitates the absorption of key micronutrients including B12, folate, iron, and zinc.
Complete Macronutrient Breakdown – Pancreatin is the pancreas's contribution to digestion — a concentrated blend of amylase (carbohydrate digestion), lipase (fat digestion), and protease (protein digestion). When the stomach acid signal is adequate, the pancreas releases these enzymes into the small intestine. When it isn't, pancreatin production drops and macronutrient digestion becomes incomplete.
Unlock Your Fat-Soluble Nutrients – Bile emulsifies dietary fats and is the essential vehicle for absorbing fat-soluble vitamins A, D, E, and K, as well as CoQ10 and omega-3 fatty acids. Athletes who have had their gallbladder removed lose the bile reservoir entirely — but even those with an intact gallbladder can have compromised bile output from chronic low stomach acid. Ox bile concentrate in this formula directly fills that gap, enabling full absorption of the fat-soluble micronutrients your body depends on for immunity, bone health, and cardiovascular function.
Together these five ingredients — betaine HCL, L-glutamic acid HCL, pepsin, pancreatin, and ox bile — replicate the complete digestive enzyme environment that your body produces from mouth to small intestine. This is broad-spectrum support, not just an antacid or a single-enzyme product.
How to Use Thorne Advanced Digestive Enzymes
With Every Meal: Take 1–2 capsules with each meal, or as recommended by your healthcare practitioner. The capsules work during active digestion — taking them at the start of a meal is ideal.
Adjust by Meal Size and Composition: Larger meals — especially those high in protein or fat — may benefit from 2 capsules. Lighter meals may need only 1. Let your digestive response guide your dose.
Pro Tip: Do not open the capsule or remove the powder — betaine HCL and L-glutamic acid HCL are irritating to the mouth and esophagus. Always swallow whole.
